Review ArticlesThe Echogenic Liver Steatosis and BeyondWu, Markus MD; Sharma, Priya G. MD; Grajo, Joseph R. MD Author Information Department of Radiology, University of Florida College of Medicine, Gainesville, FL. Received for publication February 2, 2020; accepted April 28, 2020. The authors declare no conflict of interest. Address correspondence to: Joseph R. Grajo, MD, Department of Radiology, University of Florida College of Medicine, 1600 SW Archer Rd, Box 100374, Gainesville, FL 32610 (e-mail: [email protected]). Ultrasound Quarterly 37(4):p 308-314, December 2021. | DOI: 10.1097/RUQ.0000000000000510 Buy Metrics Abstract Ultrasound is the most common modality used to evaluate the liver. An echogenic liver is defined as increased echogenicity of the liver parenchyma compared with the renal cortex. The prevalence of echogenic liver is approximately 13% to 20%. In most clinical settings, increased liver echogenicity is simply attributed to hepatic steatosis. It is important to recognize other hepatic and systemic diseases including cirrhosis, viral hepatitis, glycogen storage disease, and hemochromatosis that may also cause an echogenic liver and to identify the associated findings to distinguish them from hepatic steatosis. Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.