Effects of a broad-spectrum caspase inhibitor and volume-regulatory Cl− channel inhibitors on FS of the left ventricle at 24 hr after reperfusion. Global warm I/R markedly decreased the FS after 24 hr of reperfusion (warm I/R [24 hr]), which was improved by these inhibitors to nearly the level with global cold ischemia followed by 24 hr of reperfusion (cold I/R [24 hr]). The FS was measured by ultrasound cardiography through the abdominal walls of the recipient rats. Mean±SE for 6 rats. *P <0.005 vs. warm I/R (24 hr).