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Endovascular Stapler Failure Necessitating Cardiopulmonary Resuscitation of the Donor After Laparoscopic Donor Nephrectomy

Yoo, Koo Han; Min, Gyeong Eun

doi: 10.1097/TP.0b013e3182558f89
Letter to the Editor
Free

Department of Urology School of Medicine Kyung Hee University Seoul, Korea

The authors declare no funding or conflicts of interest.

Address correspondence to: Koo Han Yoo, M.D., Ph.D., Department of Urology, School of Medicine, Kyung Hee University, 149 Sangil-Dong, Gangdong-Gu, Seoul 134-727, Korea.

E-mail: yookoohan@khu.ac.kr

Received 24 February 2012. Revision requested 4 March 2012.

Accepted 13 March 2012.

Endovascular staplers are widely used to manage vessels in laparoscopic donor nephrectomy because of their feasibility and safety. During operation, stapler use may decrease warm ischemia time compared with Hem-o-lok (Research Triangle Park, Durham, NC) or titanium clips (1). Right-sided laparoscopic donor nephrectomy using staplers allows safe and feasible harvest of the full length of the right renal vein without compromising warm ischemia time (2). A previous report of Hem-o-lok clip dislodgement encouraged transplant surgeons to use endovascular stapler devices (3). This letter presents a case of late endovascular stapler failure requiring subsequent donor cardiopulmonary resuscitation with the goal of alerting transplant surgeons to maintain careful stapler management.

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CASE PRESENTATION

A kidney donation from a healthy 52-year-old man to his wife was approved by our hospital transplant center. Hand-assisted left donor nephrectomy was performed, and the renal artery and vein were cut using an Endo GIA 30-mm articulating vascular stapler (Autosuture; Covidien Surgical, Mansfield, MA). There was no acute bleeding in the renal pedicle area. The kidney donor was extubated in the operating room and observed in the recovery room for 2 hr. Before discharge from the recovery room, the patient was fully conscious with stable vital signs, and his hemoglobin level was 15.2 g/dL. In the ward, 8 hr after the surgery, the patient developed a minimal drop of blood pressure and a slightly rapid pulse rate. After intravenous fluid infusion, the patient’s blood pressure and pulse rate recovered briefly. At 10 hr after the surgery, the patient developed drowsy consciousness and a sudden drop of blood pressure with a hemoglobin level of 8.7 g/dL. Cardiopulmonary resuscitation was performed, and the patient was transferred to the operating room. During exploratory laparotomy through a midline incision, the left renal artery was partially opened and ligated with a suture tie. After confirmation that there was no active bleeding at the previous operative site, the exploratory laparotomy was completed. At 8 hr after the exploratory laparotomy, the patient showed stable vital signs and alert mentality. At 14 days after the second surgery, the patient remained stable, and his serum creatinine level was 1.5 mg/dL.

A video of the laparoscopic donor nephrectomy showed that three-row vascular staples remained in perfection after stapling the renal vessels. However, there was partial tearing of several staples securing the main renal artery. Dekel et al. (3) previously reported that pain-related adrenergic stimuli associated with temporarily elevated blood pressure could cause clip dislodgment from an arterial stump. This mechanism may also explain the findings in the present case. Endovascular stapler malfunctions have been reported during laparoscopic nephrectomy (4–8). Of 2078 cases reported in 5 previous studies, 22 (1.05%) stapler malfunctions requiring transfusion or open conversion were reported.

Ligation of renal vessels for laparoscopic donor nephrectomy is critical. Double Hem-o-lok clipping, double titanium clipping, or single stapling of the renal artery may cause problems in some cases. The use of a single medium-large titanium clip distal to a single 10-mm Hem-o-lok clip near the root of the aorta may be appropriate to ensure adequate tightness of the renal artery ligation (9). Combinations of methods should be carefully studied to improve the safety of each method.

Koo Han Yoo

Gyeong Eun Min

Department of Urology

School of Medicine

Kyung Hee University

Seoul, Korea

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REFERENCES

1. Bittner JG 4th, Sajadi K, Brown JA. Comparison of renal artery occlusion techniques in hand-assisted laparoscopic living donor nephrectomy. J Endourol 2009; 23 (6): 933.
2. Bollens R, Mikhaski D, Espinoza BP, et al.. Laparoscopic live donor right nephrectomy: a new technique to maximize the length of the renal vein using a modified Endo GIA stapler. Eur Urol 2007; 51 (5): 1326.
3. Dekel Y, Mor E. Hem-o-lok clip dislodgment causing death of the donor after laparoscopic living donor nephrectomy. Transplantation 2008; 86 (6): 887.
4. Chan D, Bishoff JT, Ratner L, et al.. Endovascular gastrointestinal stapler device malfunction during laparoscopic nephrectomy: early recognition and management. J Urol 2000; 164 (2): 319.
5. Deng DY, Meng MV, Nguyen HT, et al.. Laparoscopic linear cutting stapler failure. Urology 2002; 60 (3): 415.
6. Breda A, Veale J, Liao J, et al.. Complications of laparoscopic living donor nephrectomy and their management: the UCLA experience. Urology 2007; 69 (1): 49.
7. Hsu TH, Su LM, Ratner LE, et al.. Renovascular complications of laparoscopic donor nephrectomy. Urology 2002; 60 (5): 811.
8. Ko EY, Castle EP, Desai PJ, et al.. Utility of the endovascular stapler for right-sided laparoscopic donor nephrectomy: a 7-year experience at Mayo Clinic. J Am Coll Surg 2008; 207 (6): 896.
9. Simforoosh N, Aminsharifi A, Zand S, et al.. How to improve the safety of polymer clips for vascular control during laparoscopic donor nephrectomy. J Endourol 2007; 21 (11): 1319.
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