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European Reflections on New Indications for Extracorporeal Photopheresis in Solid Organ Transplantation

Ahrens, Norbert, MD1; Geissler, Edward K., PhD2; Witt, Volker, MD3; Berneburg, Mark, MD4; Wolff, Daniel, MD5; Hirt, Stephan W., MD6; Banas, Bernhard, MD7; Schlitt, Hans J., MD2; Hutchinson, James A., MBBChir, PhD2

doi: 10.1097/TP.0000000000002244
Original Basic Science—General

Extracoroporeal photopheresis (ECP) is beneficial in GVHD and rejection in solid organ transplantation in certain situations. This manuscript calls for standardization of ECP technical procedures, implementing quality-control assays and reporting of clinical outcomes as well as understanding mechanisms of action.

1 Institute for Clinical Chemistry and Laboratory Medicine, Transfusion Medicine, University Hospital Regensburg, Regensburg, Germany.

2 Department of Surgery, University Hospital Regensburg, Regensburg, Germany.

3 St. Anna Kinderspital, Medical University of Vienna, Vienna, Austria.

4 Department of Dermatology, University Hospital Regensburg, Regensburg, Germany.

5 Department of Internal Medicine III, University Hospital Regensburg, Regensburg, Germany.

6 Department of Cardiothoracic Surgery, University Hospital Regensburg, Regensburg, Germany.

7 Department of Nephrology, University Hospital Regensburg, Regensburg, Germany.

Received 11 July 2017. Revision received 8 March 2018.

Accepted 22 March 2018.

The authors declare no funding or conflicts of interests.

N.A., E.K.G., V.W., M.B., D.W., S.W.H., B.B., H.J.S., and J.A.H. participated in writing of this article.

Correspondence: Norbert Ahrens, MD Institute for Clinical Chemistry and Laboratory Medicine, Transfusion Medicine, University Hospital Regensburg, Franz-Josef-Strauß-Allee 11, 93053 Regensburg, Germany. (norbert.ahrens@ukr.de).

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