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Systemic Infections Caused by Escherichia Coli in a Neutropenic Patient With Multiple TLR Gene Polymorphisms Abolished by Stem-Cell Transplantation

Rossini, Giada1; Stanzani, Marta2; Baccarani, Michele2; Tolomelli, Giulia2; Landini, Maria P.1; Sambri, Vittorio1,3; Varani, Stefania1,4

doi: 10.1097/TP.0b013e31820cfdad
Letters to the Editor

SUPPLEMENTAL DIGITAL CONTENT IS AVAILABLE IN THE TEXT.

1 Unit of Microbiology; Department of Hematology and Oncology “L. and A. Seragnoli”; St. Orsola Hospital; University of Bologna; Bologna, Italy (Rossini, Landini, Sambri, Varani)

2 Unit of Hematology; Department of Hematology and Oncology “L. and A. Seragnoli”; St. Orsola Hospital; University of Bologna; Bologna, Italy (Stanzani, Baccarani, Tolomelli)

3 National Institute of Biosystems and Biostructures; Bologna, Italy (Sambri)

4 Division of Clinical Microbiology; Department of Laboratory Medicine; Karolinska University Hospital; Huddinge, Sweden (Varani)

Address correspondence to: Vittorio Sambri, M.D., PhD., Unit of Microbiology, Department of Hematology and Oncology “L. and A. Seragnoli,” St. Orsola Hospital, 9 via Massarenti, 40138 Bologna, Italy.

E-mail: vittorio.sambri@unibo.it

G.R., S.V., and V.S. participated in the research design. G.R., M.S., and S.V. participate in writing of the manuscript. G.R. and G.T. participated in the performance of the research. G.R., M.S., M.B., M.P.L., S.V., and V.S. participated in data analysis.

This work was supported by the Italian Ministry of University and Scientific Research (PRIN 2007) (M.P.L.), “Fondi Finalizzati C.R.R.E.M.” from Regione Emilia Romagna (V.S.), and RFO 2008 from University of Bologna (S.V., M.P.L., and V.S.).

The authors declare no conflict of interest.

Supplemental digital content is available for this article. Direct URL citations appear in the printed text, and links to the digital files are provided in the HTML text of this article on the journal's Web site (www.transplantjournal.com).

Received 17 November 2010. Revision requested 7 December 2010.

Accepted 22 December 2010.

© 2011 Lippincott Williams & Wilkins, Inc.