1Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark.
2Department for Clinical Medicine – Comparative Medicine Lab, Aarhus University, Aarhus, Denmark.
3Department for Cardiothoracic Surgery, University Medical Centre Groningen, Groningen, the Netherlands.
4Department for Cardiothoracic Surgery, Aarhus University Hospital, Aarhus, Denmark.
5Department for Anesthesiology, Region Hospital Silkeborg, Silkeborg, Denmark.
6Department for Anesthesiology, Hospital Unit West, Herning, Denmark.
7Research Unit for Molecular Medicine, Institute for Clinical Medicine, Aarhus University, Aarhus, Denmark.
8Department for Cardiothoracic Surgery, Royal Papworth Hospital NHS Foundation Trust, Cambridge, United Kingdom.
Received 3 January 2022. Revision received 14 February 2022.
Accepted 9 March 2022.
*These authors share co-first authorship.
N.M. received a scholarship from Aarhus University. Novo Nordisk, Independent Research Foundation Denmark, and Maersk Foundation also generously supported the study.
The authors declare no conflicts of interest.
All authors agree with the content of the manuscript and have made substantial contributions to the work; N.M., L.I., P.R., M.P., S.T., and H.E. conceived and planned the experiments, and N.M., L.Z., and C.C. carried out the experiments. J.P. performed analysis of inflammatory markers. N.M., M.P., and H.E. interpreted the results, and L.Z., L.I., P.R., M.E., and S.T. contributed to the surgical protocol and provided constructive feedback. N.M. wrote the first draft of the manuscript. All authors provided critical feedback and helped shape the research, analysis, and manuscript.
The data that support the findings of this study are available from the corresponding author upon reasonable request.
Supplemental Visual Abstract; https://links.lww.com/TP/C425.
Supplemental digital content (SDC) is available for this article. Direct URL citations appear in the printed text, and links to the digital files are provided in the HTML text of this article on the journal’s Web site (www.transplantjournal.com).
Correspondence: Niels Moeslund, MD, Cardiology Research – Department of Clinical Medicine, Aarhus University, Palle Juul-Jensens Boulevard 99, 8000, Aarhus N, Denmark. ([email protected]).
