1 Department of Surgery, University of Alberta, Edmonton, AB, Canada.
2 National Institute of Medical Sciences and Nutrition Salvador Zubiran, Mexico City, Mexico.
3 CHRISTUS-LatAm Hub—Excellence and Innovation Center, Monterrey, Mexico.
4 Clinical Islet Transplant Program, University of Alberta, Edmonton, AB, Canada.
5 Department of Medicine, Division of Endocrinology, University of Alberta, Edmonton, AB, Canada.
6 Alberta Diabetes Institute, Edmonton, AB, Canada.
Received 4 May 2022. Revision received 22 June 2022.
Accepted 11 July 2022.
A.M.J.S. is supported through a Canada Research Chair (Tier 1) in Regenerative Medicine and Transplant Surgery and through grant support from the Juvenile Diabetes Research Foundation, Diabetes Canada, The Canadian Donation and Transplant Research Project, the Diabetes Research Institute Foundation of Canada, the Alberta Diabetes Foundation, and the Canadian Stem Cell Network. A.M.J.S. serves as a consultant to ViaCyte Inc, Aspect Biosystems Inc, and ProtoKinetix Inc. B.A.M.-G. is currently supported by the Patronage of the National Institute of Medical Sciences and Nutrition Salvador Zubirán by the Foundation for Health and Education Dr Salvador Zubirán (FunSaEd) and the CHRISTUS-LatAm Hub—Excellence and Innovation Center. P.A.S. holds the Charles A. Allard Chair in Diabetes Research. P.A.S. and A.L. are supported by Alberta Health through the Academic Medicine and Health Services Program. The other authors declare no conflicts of interest.
K.V. and B.A.M.-G. participated in writing the article, performance of the research, study design, and data analysis. K.D., D.L.B., B.A., T.K., A.L., D.O., and P.A.S. participated in editing the article, performance of procedures discussed in the research, and study design. A.M.J.S. provided study oversight and conceptualization and participated in writing and editing the article, performance of procedures discussed in the research, and study design.
No additional data beyond the included figures and tables in this article are available or published elsewhere.
Supplemental Visual Abstract; https://links.lww.com/TP/C590.
Supplemental digital content (SDC) is available for this article. Direct URL citations appear in the printed text, and links to the digital files are provided in the HTML text of this article on the journal’s Web site (www.transplantjournal.com).
Correspondence: A. M. James Shapiro, MD, PhD, FRCS (Eng), FRCSC, MSM, Fellow of the Royal Society of Canada, Canada Research Chair in Transplant Surgery and Regenerative Medicine, Professor of Surgery, Medicine and Surgical Oncology, University of Alberta, Director Clinical Islet and Living Donor Liver Transplant Program, University of Alberta, 1-002 Li Ka Shing Centre for Health Research Innovation, 112 St NW & 87 Ave NW, Edmonton, AB, Canada T6G 2E1. ([email protected]).