Roxelyn and Richard Pepper Department of Communication Sciences and Disorders, Northwestern University, Evanston, Illinois (Dr Roberts and Mss Aveni, Gutierrez, and Chen); School of Communication Sciences and Disorders, Canadian Center for Activity and Aging (Ms Basque and Dr Orange), and Department of Clinical Neurological Sciences, London Health Sciences Center, (Dr Mandzia), Western University, London, Ontario, Canada; Centre for Neuroscience Studies (Dr Kwan), Queen's University (Dr McLaughlin), Kingston, Ontario, Canada; Sunnybrook Research Institute (Drs Ramirez and Black) and Department of Neurology (Dr Swartz), Sunnybrook Health Sciences Center (Mr Scott and Dr Symons), Toronto, Ontario, Canada; Neuropsychology and Cognitive Health (Dr Troyer) and Rotman Research Institute (Drs Binns, Levine, and Strother and Ms Sunderland), Baycrest Health Sciences, Toronto, Ontario, Canada; Department of Psychology (Dr Troyer), Dalla Lana School of Public Health (Dr Binns), Department of Medicine (Drs Black and Casaubon), Departments of Psychology and Medicine (Neurology) (Dr Levine), Department of Medical Biophysics (Dr Strother), Department of Medical Imaging (Dr Symons), and Department of Medicine (Neurology) (Dr Swartz), University of Toronto, Toronto, Ontario, Canada; Robarts Research Institute and Department of Medical Biophysics, University of Western Ontario, London, Ontario, Canada (Dr Bartha); Toronto Western Hospital, Toronto, Ontario, Canada (Dr Casaubon); Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada (Dr Dowlatshahi); Ottawa Hospital Research Institute, Ottawa, Ontario, Canada (Dr Dowlatshahi); Thunder Bay Regional Health Science Center, Thunder Bay, Ontario, Canada (Dr Hassan); Department of Medicine, McMaster University, Hamilton, Ontario, Canada (Dr Sahlas); and Ontario Neurodegenerative Disease Research Initiative Investigators (Dr Swartz).
Corresponding Author: Angela Roberts, PhD, Roxelyn and Richard Pepper Department of Communication Sciences and Disorders, Northwestern University, 2240 Campus Dr, Evanston, IL 60208 (angela.rob[email protected]).
This research was conducted with the support of the Ontario Brain Institute, an independent nonprofit corporation, funded partially by the Ontario government. The opinions, results, and conclusions are those of the authors and no endorsement by the Ontario Brain Institute is intended or should be inferred. Matching funds were provided by participant hospital (recruitment sites) and research institute foundations, including the Baycrest Foundation, Bruyere Research Institute, Centre for Addiction and Mental Health Foundation, London Health Sciences Foundation, McMaster University Faculty of Health Sciences, Ottawa Brain and Mind Research Institute, Queen's University Faculty of Health Sciences, the Sunnybrook Foundation, the Thunder Bay Regional Health Sciences Centre, the University of Ottawa Faculty of Medicine, and the Windsor/Essex County ALS Association. The Temerty Family Foundation provided the major infrastructure matching funds. This work also was supported by research grants to the first author (A.R.) from the National Institutes of Deafness and Communication Disorders 1R21DC017255-01, the Canadian Institutes of Health Research (Fellowship in Aging), and Parkinson's Canada.
The authors acknowledge ONDRI's clinical coordinators and other research team members including Catarina Downey, Heather Hink, Donna McBain, Lindsey McLeish, and Alicia J. Peltsch. The authors acknowledge K. B. Zaidi (York University) for her invaluable input in selecting criteria for the participant cognitive classification. The authors gratefully acknowledge the following students and trainees from Northwestern University and Western University who were involved in the transcription and annotation procedures: Chelsea Avery, Mackenzie Barber, Emily Bernie, Emma Carruthers, Sarah Culbert, Michelle Egan, Marissa Esparza, Melissa Fiocchi, Allison Fletcher, Casey Hamilton, Sabreen Hassib, Hannah Hinkle, Paula Ignaciuk, Brianna Jones, Alison Klassen, Tara Lewis, Bridget Maloney, Natalie Melick, Maria Ostia, Meaghan Prouse, Connor Spence, and Kelsey Wardrop.
Data will be available to researchers for purposes of reproducing the results or replicating the procedures. Available data files are detailed in Supplemental Digital Content file S1 (available at: https://links.lww.com/TLD/A72). De-identified data files and orthographic transcripts used in the reported analyses will be released through Brain-CODE (Vaccarino et al., 2018; https://www.braincode.ca) beginning fall 2020. Data governance and access requests will be managed by ONDRI and the Ontario Brain Institute. Audio files of spoken discourse samples will not be available to the general scientific community in compliance with data use as consented to by participants. Study analytical software used in the discourse analysis (SALT) is available at www.saltsoftware.com. Stimuli for eliciting spoken discourse and other source materials for the study are available through various published resources (references noted in the article). The reported study protocol was not preregistered with an independent, institutional registry.
Author disclosures can be found at https://links.lww.com/TLD/A73.
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