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The Basics of Antithrombotic Medications

How Do They Work and Why Should We Care?

Neville, Kevin, PT, DPT, CCS

Topics in Geriatric Rehabilitation: January/March 2019 - Volume 35 - Issue 1 - p 55–71
doi: 10.1097/TGR.0000000000000216
Pharmacology for the Older Adult: A Primer for the Fine Print
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Drugs used to treat or prevent thromboembolic disease are a common cause of adverse drug reactions in older adults. The purpose of this review is to provide rehabilitation professionals working with older adults with an understanding of the basics of antithrombotic drug therapy. By gaining familiarity with hemostasis and mechanisms of action of common drugs, therapists can more easily understand the adverse effects of these medications, how patients are monitored, and how drugs are reversed. Most importantly, this review provides readers with insight into the impact of these drugs on clinical decision-making in the rehabilitation of older adults.

Department of Physical Therapy Education, College of Health Professions, State University of New York Upstate Medical University, New York 13210.

Correspondence: Kevin Neville, PT, DPT, CCS, Department of Physical Therapy Education, College of Health Professions, State University of New York Upstate Medical University, 750 East Adams St, Syracuse, NY 13210 (nevillek@upstate.edu).

The author has no financial, consultant, institutional, or other relationships with any entities named in this article that might lead to a conflict of interest. No funding was received in support of this article.

Copyright © 2019 Wolters Kluwer Health, Inc. All rights reserved.