CURRENT CLINICAL NUTRITION ISSUES: PDF OnlyDietary Restriction, Aging and Disease Prevention A Discussion of Human ApplicationAspnes, Lauren E. BS, RD1; Kim, Moon-Ju MS2; Weindruch, Richard PhD3Author Information 1Research Assistant Department of Nutritional Sciences 2Research Assistant Department of Nutritional Sciences 3Professor Department of Medicine, Institute on Aging, and Veterans Administration Geriatric Research Education and Clinical Center University of Wisconsin Madison, Wisconsin Dr. Weindruch's research is supported by the National Institute on Aging (P01 11915, R01 10536), the American Cancer Society (CN-57), and the Veterans Administration. Topics in Clinical Nutrition: June 1997 - Volume 12 - Issue 3 - p 76-83 Buy Abstract It has been known for more than 60 years that restricting calories without causing malnutrition decreases disease incidence and extends maximum life span in many diverse species. Recently, investigators have begun to address the feasibility of using dietary restriction in humans. This article provides a brief overview of the history of dietary restriction and a discussion of its potential use in human populations. © 1997 Aspen Publishers, Inc.