NARRATIVE REVIEWA Systematic Review of the Role of Thiamine Supplementation in Treatment of Refeeding SyndromeSteiner, Lea MS, RD, CSG; Hewlings, Susan PhD, RDAuthor Information Boise Veterans Affairs Medical Center, Boise, Idaho. Correspondence: Lea Steiner, MS, RD, CSG ([email protected]). The authors have disclosed that they have no significant relationships with, or financial interest in, any commercial companies pertaining to this article. Topics in Clinical Nutrition: January/March 2021 - Volume 36 - Issue 1 - p 36-51 doi: 10.1097/TIN.0000000000000235 Buy Metrics Abstract The purpose of this systematic review is to identify studies where measurable thiamine supplementation was provided to patients at risk for or with refeeding syndrome to improve treatment guidelines. A systematic review of PubMed and CINAHL Plus databases was conducted using the terms refeeding syndrome, hypophosphatemia, thiamine, and vitamin B1. A total of 173 articles were retrieved and 11 case studies and 1 retrospective study met inclusion criteria. All studies identified symptoms of thiamine deficiency, and all studies indicated thiamine supplementation was associated with improved clinical symptoms and no harmful outcomes. Average dose provided was 173-mg thiamine/day. © 2021 Wolters Kluwer Health, Inc. All rights reserved.