PRACTICE PROJECTThe Effect of Probiotic Supplementation on Glycemic Control in Women With Gestational Diabetes Mellitus A Systematic ReviewKoczarski, Molly MS, RDAuthor Information Central Michigan University, Mount Pleasant. Correspondence: Molly Koczarski, MS, RD, Central Michigan University, 100 Rose Ctr, Mount Pleasant, MI 48859 (firstname.lastname@example.org). The author certifies that there are no affiliations with or involvement in any organization or entity with any financial interest, or nonfinancial interest in the subject matter or materials discussed in this review. Topics in Clinical Nutrition: July/September 2020 - Volume 35 - Issue 3 - p 270-276 doi: 10.1097/TIN.0000000000000219 Buy Metrics Abstract Benefits of probiotic supplementation for symptoms associated with gestational diabetes are limited. The purpose of this review was to investigate the effects of probiotic supplementation on glycemic control in women with gestational diabetes mellitus (GDM). A systematic search for randomized controlled trials (RCTs) reporting probiotic supplementation in GDM patients (2000 through 2019) yielded 65 articles. Eight RCTs met the criteria for inclusion. Probiotics decreased fasting plasma glucose and serum insulin levels. Significant effects were found on insulin resistance, insulin sensitivity, and lipid profiles. Probiotic supplementation may improve glycemic control, insulin resistance, and lipid profiles; more research is needed. © 2020 Wolters Kluwer Health, Inc. All rights reserved.