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Temporal Distribution of Carbohydrate and Calorie Intake Is Not Associated With Hemoglobin A1c in Persons With Type 2 Diabetes Mellitus

Petr, Jane Erin, MS, RD, LDN; Keim, Kathryn S., PhD, RD, LDN; Chapman-Novakofski, Karen M., PhD, RD, LDN; Rasmussen, Heather, PhD, RD, LDN

doi: 10.1097/TIN.0000000000000174
Clinical Dietetics Projects

The aim of this study was to examine the temporal distribution of carbohydrate and energy intake over 24 hours in individuals with type 2 diabetes mellitus and determine the association with hemoglobin A1C (A1C). Up to four 24-hour food recalls were collected from 98 subjects with type 2 diabetes mellitus. Temporal macronutrient distribution was operationalized by dividing each day into four, 6-hour time periods and calculating the percentage of total intake in each period. Linear regression was conducted to determine the extent to which these distribution patterns predicted A1C. The temporal distribution of calories and carbohydrate was not associated with A1C in this sample.

Rush University Medical Center, Chicago, Illinois (Ms Petr and Dr Keim); University of Illinois Urbana-Champaign (Dr Chapman-Novakofski); and University of Nebraska–Lincoln (Dr Rasmussen).

Correspondence: Jane Erin Petr, MS, RD, LDN, Rush University Medical Center, 1653 W Congress Pkwy, Chicago, IL 60612 (

The authors have disclosed that they have no significant relationships with, or financial interest in, any commercial companies pertaining to this article.

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