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The Link Between Vitamin D and Hepatitis B

Sum, Simon Siu-Man MS, MPhil, RD, ACSM-CPT; Bruno, Maura DCN, RD, CDE

doi: 10.1097/TIN.0000000000000030
Narrative Review

Chronic hepatitis B is caused by hepatitis B virus infection, which can adversely affect liver function. Vitamin D is an essential fat soluble vitamin for the human body, and the liver is an important organ in the conversion process of vitamin D into its active form, calcitriol. This article discusses the link between vitamin D status and the pathophysiology of hepatitis B viral infection, and whether vitamin D supplementation should be recommended to improve prognosis of hepatitis B viral infection. Evidence-based research is needed to determine the need of vitamin D supplementation for patients with chronic hepatitis B.

School of Health Related Professions, Rutgers University, Newark, New Jersey.

Correspondence: Simon Siu-Man Sum, MS, MPhil, RD, ACSM-CPT, School of Health Related Professions, Rutgers University, Stanley Bergen Bldg, 65 Bergen St, Room 157, Newark, NJ 07101 (

It is declared that the first author (Simon Siu-Man Sum) is currently employed full time as Manager of Scientific Affairs at Herbalife International of America, Inc, and a doctorate student at Rutgers University. The second author (Maura Bruno) is a faculty at Rutgers University.

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