REVIEWSRole of Omega-3 Fatty Acids in the Risk and Treatment of Breast CancerJanos, Abby L. MS, RD; Logomarsino, John V. PhD, RD, LD/N Author Information Department of Human Environmental Studies, Central Michigan University, Mount Pleasant. Correspondence: John V. Logomarsino, PhD, RD, LD/N, Department of Human Environmental Studies, Central Michigan University, Mt Pleasant, MI 48859 ([email protected]). The authors have disclosed that they have no significant relationships with, or financial interest in, any commercial companies pertaining to this article. Topics in Clinical Nutrition: July/September 2011 - Volume 26 - Issue 3 - p 246-256 doi: 10.1097/TIN.0b013e3182260ecf Buy Metrics Abstract More than one-third of cancers can be directly related to components in the diet. Breast cancer is sensitive to dietary changes and can be affected by consumption of omega-3 polyunsaturated fatty acids. Research studies show higher incidence and mortality rates of breast cancer in Western countries compared with Eastern countries because of variations in dietary practices. The ratio of omega-6 to omega-3 polyunsaturated fatty acids is essential when trying to reduce the incidence of breast cancer. Omega-6 polyunsaturated fatty acids may aid in the growth of mammary tumors, while omega-3 polyunsaturated fatty acids can reduce growth effects. © 2011 Lippincott Williams & Wilkins, Inc.