Reports of ResearchReconsidering KwashiorkorOsorio, Snezana Nena MDAuthor Information Department of Pediatrics, The New York Presbyterian Hospital-Weill Cornell Medical College, New York City. Snezana Nena Osorio, MD, Department of Pediatrics, The New York Presbyterian Hospital-Weill Cornell Medical College, New York, 525 E 68th St, PO Box 139, NY 10065 (firstname.lastname@example.org). The author thanks Dr Charles Mueller for the contributions to the shape and substance of this article, which have been substantially improved because of his thoughtful critique. This research was supported by grant ULI RR024996 of the Clinical and Translational Science Center at Weill Cornell Medical College. Topics in Clinical Nutrition: January/March 2011 - Volume 26 - Issue 1 - p 10-13 doi: 10.1097/TIN.0b013e318209e3b6 Buy Metrics Abstract Kwashiorkor is a syndrome seen in children almost exclusively in association with famine in the tropics. It is characterized by rapid development of edema, hypoalbuminemia, and distinct skin dyspigmentation. Kwashiorkor presents a number of paradoxes; it is confined to pediatric populations in the underdeveloped world and within communities with comparable living standards in isolated households. However, the exact etiology of kwashiorkor is still unknown. Various infectious agents, toxins, and prooxidants have been all implicated in the pathophysiology of this complex condition. Inflammation from infectious stimulus probably has a crucial role in the development of kwashiorkor. © 2011 Lippincott Williams & Wilkins, Inc.