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June 2023 - Volume 48 - Issue 6
pp: 5-48
Table of Contents Outline
Contributor Index

Editor's Memo

Up to Date: What's New

Medication Update

HYPERTENSION: NCPD Connection

Obesity-related hypertension: Implications for advanced nursing practice

Benenson, Irina; Prado, Kimberly

The Nurse Practitioner. 48(6):8-15, June 2023.

Obesity increases the risk of hypertension and other cardiometabolic comorbidities. Lifestyle modifications are usually recommended, though lasting effects on weight and BP reduction are limited. Weight-loss medications, especially incretin mimetics, are effective for short- and long-term treatment. Metabolic surgery provides cure of obesity-related hypertension in some patients. NPs are well positioned to manage obesity-related hypertension to improve clinical outcomes of affected individuals.

GASTROINTESTINAL DISEASES: NCPD Connection

Mesenteric ischemia in the acute care setting

Bagley, Kimberly; Schuller, Jana Grissom

The Nurse Practitioner. 48(6):17-25, June 2023.

Mesenteric ischemia is a group of disorders requiring prompt identification, supportive care, and treatment. Chronic mesenteric ischemia can develop into acute mesenteric ischemia, which has high mortality. Acute mesenteric ischemia can be occlusive (caused by arterial embolism, arterial thrombosis, or mesenteric venous thrombosis) or nonocclusive, with treatment depending on the underlying cause.

VENOUS THROMBOEMBOLISM

Direct oral anticoagulant drugs for the management of venous thromboembolism

Thanavaro, Joanne L.

The Nurse Practitioner. 48(6):27-35, June 2023.

Direct oral anticoagulants (DOACs) are effective for both prevention and treatment of venous thromboembolism (VTE) and have favorable safety in comparison with warfarin. Although drug-drug interactions with DOACs are not as frequent as with warfarin, certain drugs can interfere with DOAC metabolism, affect DOAC efficacy, and potentially cause adverse reactions when used in combination with DOACs. The NP must determine which agent is most beneficial for the individual patient with VTE based on a number of factors. A knowledge of periprocedural management of DOACs will assist the NP in providing a smooth transition for patients undergoing minor and major procedures and surgeries.

DYSLIPIDEMIA

Pharmacotherapeutics for dyslipidemia management

El Hussein, Mohamed Toufic; Sharma, Aditi; Parmar, Komal; More

The Nurse Practitioner. 48(6):36-47, June 2023.

Effective management of dyslipidemia is of paramount importance to prevent cardiovascular (CV) complications. Using current clinical practice guidelines is recommended to correct lipid levels and prevent further pathologic processes. This article presents an overview of treatment options for patients with dyslipidemia and CV disease, with a special focus on the following drug classes: HMG-CoA reductase inhibitors (also called statins), cholesterol absorption inhibitors (ezetimibe), bile acid sequestrants, fibrates, icosapent ethyl, and PCSK9 inhibitors.