Web Exclusive Content: Pictorial EssayCOVID-19 and its Mimics What the Radiologist Needs to KnowHanfi, Sameer H. MBBS; Lalani, Tasneem K. MD; Saghir, Amina MD; McIntosh, Lacey J. DO, MPH; Lo, Hao S. MD; Kotecha, Hemang M. DOAuthor Information University of Massachusetts Medical School, UMass Memorial Medical Center, Worcester, MA The authors declare no conflicts of interest. Correspondence to: Sameer H. Hanfi, MBBS, Department of Radiology, University of Massachusetts Medical School, 55 North Lake Ave, Worcester, MA 01655 (e-mail: [email protected]). Journal of Thoracic Imaging: January 2021 - Volume 36 - Issue 1 - p W1-W10 doi: 10.1097/RTI.0000000000000554 Buy Metrics Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for the current outbreak of Coronavirus disease 2019 (COVID-19). Although imaging should not be used for first-line screening or diagnosis, radiologists need to be aware of its imaging features, and those of common conditions that may mimic COVID-19 pneumonia. In this Pictorial Essay, we review frequently encountered conditions with imaging features that overlap with those that are typical of COVID-19 (including other viral pneumonias, chronic eosinophilic pneumonia, and organizing pneumonia), and those with features that are indeterminate for COVID-19 (including hypersensitivity pneumonitis, pneumocystis pneumonia, diffuse alveolar hemorrhage, pulmonary edema, and pulmonary alveolar proteinosis). Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.