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Computed Tomography and Echocardiography in Patients With Acute Pulmonary Embolism: Part 1Correlation of Findings of Right Ventricular Enlargement

Wake, Nicole MS; Kumamaru, Kanako K. MD, PhD; George, Elizabeth MBBS; Bedayat, Arash MD; Ghosh, Nina MD; Gonzalez Quesada, Carlos MD; Rybicki, Frank J. MD, PhD, FAHA, FACR; Gerhard-Herman, Marie MD

doi: 10.1097/RTI.0000000000000047
Web Exclusive Content—Original Articles

Purpose: To evaluate the correlation between the computed tomography (CT)-derived right ventricle (RV) to left ventricle (LV) diameter ratio and the RV size determined by echocardiography in patients with acute pulmonary embolism.

Materials and Methods: Consecutive CT pulmonary angiography examinations (August 2003 to May 2010) from a single, large, urban teaching hospital were retrospectively reviewed. For a cohort of 777 subjects who underwent echocardiography within 48 hours of the CT acquisition, the qualitative RV size (divided into 5 categories) extracted from the echocardiography report was correlated with the CT-derived RV/LV diameter ratio.

Results: There was moderate correlation (Spearman rank correlation coefficient=0.54, P<0.001) between the CT-derived RV/LV ratio and the RV size as determined by echocardiography. The correlation coefficient and the concordance rate were inversely related to the time difference between the acquisitions of the 2 modalities.

Conclusions: CT and echocardiography findings to assess the RV size after acute pulmonary embolism have moderate correlation.

*Department of Medicine, Cardiovascular Division

Applied Imaging Science Laboratory, Department of Radiology

§Department of Medicine, Brigham and Women’s Hospital & Harvard Medical School, Boston

Department of Radiology, University of Massachusetts Medical School, Worcester, MA

The authors declare no conflicts of interest.

Reprints: Frank J. Rybicki, MD, PhD, FAHA, FACR, Applied Imaging Science Laboratory, Department of Radiology, Brigham and Women’s Hospital & Harvard Medical School, 75 Francis Street, Boston, MA 02115 (e-mail:

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