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Evidence-based Imaging in Lung Cancer: A Systematic Review

Ravenel, James G. MD

doi: 10.1097/RTI.0b013e318254a198

Lung cancer is the leading cause of cancer-related mortality in the United States. To assess prognosis, optimize treatment, and avoid potentially harmful futile treatments it is critical to have a complete understanding of the tumor’s histology, molecular characteristics, and stage at the time of diagnosis. From the radiologist’s perspective, the goal is to provide as accurate a stage as possible before the use of minimally invasive or invasive procedures to guide the site of biopsy and confirm a final pathologic stage. This article reviews the evidence behind the imaging technologies used in the staging evaluation of lung cancer.

Department of Radiology, Medical University of South Carolina, Charleston, SC

Dr Ravenel received payment for providing testimony involving cases of lung cancer; grant funding from VuComp and payment for lectures from Novant Health Inc.

The author declares no conflicts of interest.

Reprints: James G. Ravenel, MD, Department of Radiology, Medical University of South Carolina, 96 Jonathan Lucas ST MSC323, Charleston, SC 29425 (e-mail:

© 2012 Lippincott Williams & Wilkins, Inc.