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Immune-reconstitution Syndrome Related to Atypical Mycobacterial Infection in AIDS

Berman, Erika J. MD*; Iyer, Ramesh S. MD*; Addrizzo-Harris, Doreen MD; Ko, Jane P. MD*

doi: 10.1097/RTI.0b013e3181653c25
Case Reports—Pulmonary

The immune-reconstitution syndrome is a paradoxical inflammatory response to a preexisting or a coexisting disease, after the initiation of highly active antiretroviral therapy for the human immunodeficiency virus. Infrequently described, the radiographic and computed tomographic findings of the immune-reconstitution syndrome, which is related to the Mycobacterium avium-intracellulare infection and to highly active antiretroviral therapy, are presented in 2 patients. Homogeneous mediastinal and hilar lymphadenopathy were present in both individuals, with one having a large mass accompanied by small nodules.

Departments of *Radiology

Pulmonary and Critical Care Medicine, NYU Medical Center, New York, NY

Reprints: Erika J. Berman, MD, Department of Radiology, Hospital for Joint Diseases, Room 600, New York, NY 10003 (e-mail:

© 2008 Lippincott Williams & Wilkins, Inc.