Case Reports—PulmonaryDiffuse Lung Cysts in Lymphoid Interstitial Pneumonia High-resolution CT and Pathologic FindingsSilva, C. Isabela S. MD, PhD*; Flint, Julia D. MD†; Levy, Robert D. MD‡; Müller, Nestor L. MD, PhD*Author Information Departments of *Radiology, †Pathology, Vancouver General Hospital, University of British Columbia 899 West 12th Avenue, Vancouver, BC, Canada, V5Z 1M9 ‡Respiratory Division, Vancouver General Hospital, 2775 Heather Street, Vancouver, BC, Canada V5Z 3J5 Reprints: Dr. C. Isabela S. Silva, MD, PhD, Department of Radiology, Vancouver General Hospital, 899 West 12th Avenue, Vancouver, BC, Canada V5Z 1M9 (e-mail: [email protected]). Journal of Thoracic Imaging: August 2006 - Volume 21 - Issue 3 - p 241-244 doi: 10.1097/01.rti.0000213554.61752.73 Buy Metrics Abstract Lymphoid interstitial pneumonia is part of a spectrum of pulmonary lymphoproliferative disorders that range from benign, small, and airway-centered cellular infiltrates (follicular bronchiolitis, nodular lymphoid hyperplasia) to low-grade malignant lymphoma. Most of the cases occur in patients with underlying autoimmune disease or immunodeficiency. The characteristic high-resolution computed tomography findings consist of diffuse ground-glass opacities, ill-defined centrilobular nodules, bronchovascular thickening, interlobular septal thickening, and scattered thin-walled cysts. The cysts may be seen in up to 80% of the patients and are typically few in number and measure less than 3 cm in diameter. This case illustrates extensive cysts as the predominant high-resolution computed tomography finding of idiopathic lymphoid interstitial pneumonia in a 64-year-old man who underwent unilateral lung transplant. Such extensive cystic disease and lung transplantation treatment has not been previously described. © 2006 Lippincott Williams & Wilkins, Inc.