Pictorial EssayImaging Appearance of Thoracic AmyloidosisAylwin, Anthony C. B MB ChB, MRCS, FRCR; Gishen, Philip MB ChB, DMRD, FRCR; Copley, Susan J MB BS, MRCP, MD, FRCRAuthor Information From the Department of Imaging, Hammersmith Hospital, London, UK. Reprints: Dr. Susan Copley, Department of Imaging, Hammersmith Hospital, Du Cane Road, London, W12 0HS, UK. (e-mail: [email protected]). Journal of Thoracic Imaging: February 2005 - Volume 20 - Issue 1 - p 41-46 doi: 10.1097/01.rti.0000154074.29194.09 Buy Metrics Abstract Amyloidosis is a disease caused by the deposition of abnormal proteins within extracellular soft tissues, and affects the respiratory tract in 50% of cases. Pulmonary involvement may be secondary to systemic disease or due to the accumulation of locally produced amyloid, and this differentiation has important prognostic and therapeutic implications. This pictorial essay, using cases of biopsy-proven respiratory tract amyloidosis, aims to depict the spectrum of imaging findings, and those of CT in particular, that can be of use in distinguishing between the 2 typical patterns of the disease. © 2005 Lippincott Williams & Wilkins, Inc.