Case Report/Case SeriesProtean Manifestations and Diagnostic Challenges Including Discordance Between Electrodiagnostic-Radiologic Studies in NeurolymphomatosisLorance, David K. MD; Allison, James B. MD; Gardner, Juli-Anne MD; Waheed, Waqar MDAuthor Information Department of Neurological Sciences, University of Vermont Medical Center, Burlington, VT The authors declare no conflict of interest. Correspondence to: David K. Lorance, MD, University of Vermont Medical Center, Burlington, VT 05401. E-mail: email@example.com. Online date: January 6, 2020 The Neurologist: January 2020 - Volume 25 - Issue 1 - p 4-9 doi: 10.1097/NRL.0000000000000245 Buy Metrics Abstract Introduction: Malignant lymphocytic infiltration of the central nervous system (CNS) and peripheral nervous system (PNS) is diagnostically challenging and informs treatment and prognosis. Case Report: We describe the clinical course of a 49-year-old man with CNS and PNS relapse of mantle cell lymphoma and the diagnostic modalities that enabled the diagnosis of neurolymphomatosis. Conclusion: This clinical phenotype reinforces previously reported presentations of neurolymphomatosis and the ability of multimodal diagnostics, when combined with clinical suspicion phenotype, to enable diagnosis of malignant lymphocytic infiltration of the CNS and PNS. Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.