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Successful Thrombolysis in the Setting of Marfan Syndrome and Chronic Aortic Dissection

Malek, Elia G. MD; Nasreddine, Wassim MD; Makki, Achraf MD, MSc

doi: 10.1097/NRL.0000000000000251
Case Report/Case Series

Introduction: Thrombolysis is the standard of care in acute ischemic stroke. It is usually contraindicated in patients with aortic dissection.

Case Report: We report a case of Marfan syndrome and chronic aortic dissection presenting with acute ischemic stroke treated with thrombolysis.

Conclusion: To our knowledge, this is the first case of Marfan syndrome with chronic aortic dissection undergoing thrombolysis for acute ischemic stroke with a near-complete recovery of neurological deficit and favorable long-term outcome.

Neurology Department, American University of Beirut Medical Center, Beirut, Lebanon

The authors declare no conflict of interest.

Correspondence to: Achraf Makki, MD, MSc, Neurology Department, American University of Beirut Medical Center, PO Box 11-0236, Riad El-Solh, Beirut 1107 2020, Lebanon. E-mail:

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