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PRES and Epilepsy: A Potential Long-Term Consequence of a “Reversible” Syndrome

Fitzgerald, Ryan T. MD; Santoro, Jarod BS; Hinduja, Archana MD; Samant, Rohan S. MD; Kumar, Manoj MD; Angtuaco, Edgardo J. MD

doi: 10.1097/NRL.0000000000000103
Case Report/Case Series

Epilepsy is very rarely attributed to posterior reversible encephalopathy syndrome (PRES). We report the case of a previously healthy 21-year-old who developed epilepsy with mesial temporal sclerosis following an episode of PRES related to a complicated Cesarean delivery. Neuroimaging at the time of PRES and 3 months after revealed the development of unilateral hippocampal volume loss following resolution of acute PRES-related brain edema. We discuss the incidence and importance of “non-reversible” sequelae of PRES and their implications for patient care.

Departments of *Radiology


College of Medicine, University of Arkansas for Medical Sciences, Little Rock, AR

§Department of Neurology, Ohio State University, Columbus, OH

The authors declare no conflict of interest.

Reprints: Ryan T. Fitzgerald, MD, Department of Radiology, University of Arkansas for Medical Sciences, Neuroradiology Division Slot 556, 4301 W. Markham St., Little Rock, AR 72205. E-mail:

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