Case Report/Case SeriesDelayed Intraparenchymal Hematoma Following Diagnostic Lumbar PunctureLapadula, Gennaro MD*; Caporlingua, Federico MD*; Caporlingua, Alessandro MD*; Currà, Antonio MD†; Fattapposta, Francesco MD‡; Missori, Paolo MD*Author Information Departments of *Neurology and Psychiatry, Neurosurgery †Medico-Surgical Sciences and Biotechnologies, Neurology Unit, “A. Fiorini” Hospital Terracina, LT ‡Neurology and Psychiatry, “Sapienza” University of Rome, Rome, Italy The authors declare no conflict of interest. Reprints: Federico Caporlingua, MD, Department of Neurology and Psychiatry, Neurosurgery, “Sapienza” University of Rome, Viale del Policlinico 155, Rome 00161, Italy. E-mail: [email protected]. The Neurologist: October 2015 - Volume 20 - Issue 4 - p 70-73 doi: 10.1097/NRL.0000000000000055 Buy Metrics Abstract Lumbar puncture is a safe and commonly performed procedure, with an overall complication rate of 0.1% to 0.5%. Well-known contraindications to lumbar puncture are an intracranial tumor, noncommunicating hydrocephalus, coagulopathy, and ruptured aneurysm with subarachnoid hemorrhage. We report a case of a young man with epilepsy who, after a lumbar puncture performed for research purposes, presented with an intracerebral hematoma and neurological deficits. To the best of our knowledge, post-tap intraparenchymal hematoma is extremely rare and only 1 case has been reported previously. In consideration, all patients undergoing a lumbar puncture should be informed about this possible rare complication, even in the absence of documented hemorrhagic risk factors. Copyright © 2015 Wolters Kluwer Health, Inc. All rights reserved.