Original ArticleCauda Equina and Conus Medullaris Syndrome in Sarcoidosis Case Report and Literature ReviewKaiboriboon, Kitti MD*; Olsen, Thomas J. MD†; Hayat, Ghazala R. MD* Author Information From the *Department of Neurology and the †Department of Internal Medicine, Saint Louis University, St. Louis, Missouri. Reprints: Ghazala R. Hayat, MD, Department of Neurology, 3635 Vista Avenue at Grand Boulevard, St. Louis, MO 63110-0250. E-mail: [email protected]. The Neurologist: May 2005 - Volume 11 - Issue 3 - p 179-183 doi: 10.1097/01.nrl.0000159983.19068.21 Buy Metrics Abstract Background: Neurosarcoidosis is a rare manifestation of sarcoidosis. Involvement of the nervous system in sarcoidosis can range from peripheral or cranial neuropathy to central nervous system disease. Cauda equina sarcoidosis is distinctly rare. Review Summary: The authors present a 58-year-old patient with systemic sarcoidosis who developed cauda equina and conus medullaris syndrome. Seventeen previous published cases of cauda equina sarcoidosis are reviewed. The history of systemic sarcoidosis, cerebrospinal fluid characteristics of lymphocytic pleocytosis with elevated protein, and evidence of acute denervation by needle electromyography are helpful in the diagnosis of this condition. Early diagnosis and treatment of cauda equina sarcoidosis usually provide a rapid recovery and yield a good prognosis. Conclusion: Although rare, sarcoidosis should be considered in the differential diagnosis of cauda equina syndrome, particularly in patients with unclear etiology. © 2005 Lippincott Williams & Wilkins, Inc.