is more prevalent in women
than men. Hormonal changes can influence the occurrence of migraine
, particularly related to the menstrual cycle. Menstrual migraine
may require both acute and preventive treatment.
Gender differences in migraine
may be a result of variations in the central nervous system of men and women
as well as the effects of estrogen
attacks occurring in the perimenstrual period respond well to acute treatment with triptans. Hormonal manipulation may reduce migraine
occurrence, especially when related to hormonal fluctuations in the perimenstrual period.
management requires an understanding of the unique epidemiologic and pathophysiological factors affecting women
. An understanding of associated hormonal influences facilitates development of individualized treatment plans.