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Rhabdomyolysis Due to Micronized Fenofibrate

Oguzhan, Nilufer MD; Unal, Aydin MD; Sipahioglu, Murat Hayri MD; Tokgoz, Bulent Prof.; Oymak, Oktay Prof.; Utas, Cengiz Prof.

doi: 10.1097/TEN.0b013e3181fd0370
Case Report
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Fenofibrate, a fibric acid derivative, is frequently used to treat diabetic dyslipidemia and hypertriglyceridemia alone or in combination with statins. Rhabdomyolysis is a syndrome that results from striated muscle necrosis and release of its contents into the systemic circulation and extracellular fluid. Fenofibrate-induced rhabdomyolysis is a rare clinical condition if there is not a predisposing factor such as diabetes mellitus, hypothyroidism, and renal insufficiency. In this study, we present a case of a patient who developed rhabdomyolysis after micronized fenofibrate use without known predisposing factor.

From the Division of Nephrology, Department of Internal Medicine, Erciyes University Medical School, Kayseri, Turkey.

Reprints: Aydin Unal, MD, Erciyes Üniversitesi Týp Fakültesi, Organ Nakli ve Diyaliz Hastanesi, Talas Yolu Üzeri, 38039, Kayseri, Turkey. E-mail: a.unal@erciyes.edu.tr or aydinunal2003@gmail.com.

© 2010 Lippincott Williams & Wilkins, Inc.