Jansen Syndrome With Unaccountable Severe Hypercalcemia Treated by BiphosphanateKeskin, Mehmet MD; Keskin, Ozlem MD; Kor, Deniz MD; Uyanik, Hatice MD; Aksoy, Mehmet MD; Palali, Fatih MDAuthor Information From the Department of Paediatrics, Gaziantep University, Gaziantep, Turkey. Reprints: Mehmet Keskin, MD, Department of Paediatric Endocrinology and Metabolism, Gaziantep University, 27310 Gaziantep, Turkey. E-mail: [email protected] The Endocrinologist: July/August 2010 - Volume 20 - Issue 4 - pp 160-161 doi: 10.1097/TEN.0b013e3181e9494c Buy Metrics Abstract We describe the use of pamidronate to control marked hypercalcemia in a girl with Jansen-type of metaphyseal chondrodysplasia. She was suffering from an unspecified interstitial lung disease and severe hypercalcemia. She was first treated with intravenous fluids, furosemide, calcitonin, and glucocorticoids without significant improvement, but became normocalcemic within 24 hours of receiving a single dose of pamidronate. © 2010 Lippincott Williams & Wilkins, Inc.