Diffuse Large B-Cell Lymphoma of the Thyroid Mimicking Thyroid Carcinoma: A Plea for Open Biopsy : The Endocrinologist

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CME Review Article #5

Diffuse Large B-Cell Lymphoma of the Thyroid Mimicking Thyroid Carcinoma

A Plea for Open Biopsy

Limmer, Stefan MD*; Bruch, Hans-Peter MD; Baehre, Manfred MD; Czymek, Ralf MD§; Eckmann, Christian MD

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The Endocrinologist 19(2):p 82-84, March 2009. | DOI: 10.1097/TEN.0b013e318198b427


Anaplastic thyroid carcinoma (ATC) and thyroid lymphoma (TL) are both in the differential diagnoses of a malignant thyroid tumor. With a similar history and clinical characteristics, it can often be difficult to distinguish ATC from TL. Ultimately, they can be reliably differentiated only by histopathology. This article presents 3 patients with lymphoma of the thyroid, who initially showed all the clinical signs of an ATC. Fine needle aspiration was performed in all 3 cases but did not provide a reliable pathologic diagnosis. The diagnosis of a primary TL was confirmed only by open surgical biopsy.

© 2009 Lippincott Williams & Wilkins, Inc.

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