Thyrotoxic Periodic Paralysis in 2 White Men After Treatment for Hyperthyroidism With Total Thyroidectomy and Radioactive Iodine : The Endocrinologist

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Thyrotoxic Periodic Paralysis in 2 White Men After Treatment for Hyperthyroidism With Total Thyroidectomy and Radioactive Iodine

Celebi-Onder, Songul MD; Dower, Joshua Michael MD; Jackson, Timothy Kevin MD

Author Information

From the Division of Endocrinology, Department of Medicine, West Virginia University, Morgantown, West Virginia.

Reprints: Songul Celebi-Onder, MD, Division of Endocrinology, Department of Medicine, West Virginia University, PO Box 9168, Morgantown, WV 26506-9168. E-mail: [email protected].

The Endocrinologist 17(5):p 255-257, September 2007. | DOI: 10.1097/TEN.0b013e3181578994

Abstract

We report an uncommon presentation of thyrotoxic periodic paralysis (TPP) following radioactive iodine (RAI) treatment and total thyroidectomy in 2 white men: a 24-year-old man with TPP in thyrotoxic state treated with total thyroidectomy in whom the TPP recurred after corrective surgery, and a 19-year-old man with TPP while on β-blockers and 2 weeks after the RAI treatment. In both patients, the underlying etiology of the hyperthyroidism was Graves disease. It is believed that the TPP occurred following RAI treatment and thyroidectomy because of a transient thyrotoxic state. Treatment with potassium and magnesium, and maximal doses of β-blockers ameliorated symptoms in less than 24 hours.

© 2007 Lippincott Williams & Wilkins, Inc.

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