Case ReportTuberculous Osteomyelitis of the Fifth Metatarsal Treated Using the Induced Membrane Technique: A Case ReportBellil, Mehdi PhD*,†; Ben Tekaya, Aicha PhD†,‡; Souissi, Mariem PhD*,†; Chrif, Kammoun PhD*,†; Kooli, Mondher PhD*,†; Ben Salah, Mohamed PhD*,† Author Information *Orthopedic Department, Charles Nicolle Hospital ‡Rheumatology Department, Charles Nicolle Hospital †Faculty of medicine of Tunis, University Tunis el Manar, Tunis, Tunisia Written informed consent was obtained from the patient for the publication of this case report and its accompanying images. The authors declare no conflict of interest. Address correspondence and reprint requests to Aicha Ben Tekaya, Rheumatology Department, Charles Nicolle Teaching Hospital, Boulevard du 9 Avril 1938, Tunis, Tunisia. E-mail: [email protected]. Techniques in Foot & Ankle Surgery: November 18, 2022 - Volume - Issue - 10.1097/BTF.0000000000000369 doi: 10.1097/BTF.0000000000000369 Buy PAP Metrics Abstract Tuberculous osteomyelitis of the foot, an uncommon and rare entity, accounts for <0.01% of all tuberculous localizations. Osteomyelitis secondary to tuberculosis is difficult to diagnose and treat, requiring a high suspicion index. We report a case of tuberculous osteomyelitis of the fifth metatarsal bone treated with the induced membrane technique. Here, we report the case of a 40-year-old woman with a history of immunosuppressive treatment presented with a complaint of painful swelling of the left foot. Radiographs showed osteolytic lesions of the fifth metatarsal bone. Initial biopsy suggested tuberculosis. She was surgically treated with the induced membrane technique. Histology confirmed tuberculous osteomyelitis and antituberculous treatment was initiated. Full weight-bearing was allowed after 8 months. At 24 months follow-up, all symptoms were resolved. The radiographs showed an integrated graft. In conclusion, the presence of osteolytic lesions on a plain film should rise high suspicious for a possible infection requiring biopsy, and if confirmed, mandates surgical debridement and reconstruction. The induced membrane technique offers a mean to treat infectious bone defects. Level of Evidence: Level 4. Copyright © 2022 Wolters Kluwer Health, Inc. All rights reserved.