Obstetric AnesthesiaPrevention of Spinal Anesthesia-Induced Hypotension During Cesarean Delivery by 5-Hydroxytryptamine-3 Receptor Antagonists A Systematic Review and Meta-analysis and Meta-regressionHeesen, M.; Klimek, M.; Hoeks, S. E.; Rossaint, R. Author Information Department of Anesthesia, Kantonsspital Baden, Baden, Switzerland. Survey of Anesthesiology 61(1):p 14-15, February 2017. | DOI: 10.1097/01.sa.0000513498.47139.d7 Buy Metrics Abstract (Abstracted from Anesth Analg, 123(4):977–988, 2016) Hypotension is a common complication affecting obstetric patients receiving spinal anesthesia and can lead to nausea and vomiting, altered consciousness, and increased risk of aspiration. As 5-hydroxytryptamine (5-HT3, serotonin) receptors are involved in this mechanism, studies have evaluated 5-HT3 receptor antagonists for their potential to prevent spinal anesthesia–induced hypotension. Copyright © 2017 Wolters Kluwer Health, Inc. All rights reserved.
