Laparoscopic splenectomy (LS) is generally applied for splenectomy, However, it also brings some technical challenges, especially for splenomegaly. Hand-assisted laparoscopic splenectomy (HALS) can help to overcome these drawbacks while maintaining the superiority of LS. This study was aimed to evaluate the efficacy and advantage of HALS for splenomegaly.
Between January 2014 and November 2017, 91 patients with splenomegaly in 2 surgical centers were randomly assigned to either HALS (n=45) or LS (n=46). The patients’ characteristics, intraoperative details, and the postoperative outcomes in both groups were compared.
Baseline features (sex, age, main diameter, Child-Pugh grade) of both groups had no significant difference (P<0.05). Compared with LS group, the HALS group operation time (141±46 vs. 172±43 min; P=0.001) was shorter, intraoperative blood loss [215 (122.332) vs. 230 (130.740) mL; P=0.026], hospital expenses (5.5±1.5 vs. 6.4±2.4 WanRMB; P=0.022), and conversion rate (1/45 vs. 9/46; P=0.015) were lower. However, there was no significant difference for hospital stay (6.4±2.8 vs. 6.7±3.0 d; P=0.662) and complications (15/45 vs. 12/46; P=0.893) between the 2 groups. In addition, there were no significant differences in postoperative white blood cell (10.6±2.9 vs. 10.9±3.5; P=0.747), AST [61 (47.94) vs. 57 (37.86) U/L; P=0.513], and ALT [68 (54.120) vs. 55 (36.99) U/L; P=0.302] levels.
HALS can maximize the benefits for patients, while maintaining the advantages of LS and open splenectomy. It is the ideal surgical treatment for splenomegaly.
*Department of Minimally Invasive Surgical Centre, Tianjin Nankai Hospital, Tianjin
†Department of Internal medicine, The Third People’s Hospital of Jiangxi Province
§Department of General Surgery, The Second Affiliated Hospital of Nanchang University, Nanchang, China
X.S. and Z.L. contributed equally.
Supported by National Natural Science Foundation of China (no. 81760514) and Youth Science Fund of Jiangxi Provincial Science and Technology Department (no. 20161BAB215252).
The authors declare no conflicts of interest.
Reprints: Yong Huang, PhD, Department of General Surgery, The Second Affiliated Hospital of Nanchang University, Nanchang 330006, China (e-mail: email@example.com).
Received May 2, 2018
Accepted December 31, 2018