The purpose of this study was to investigate scientific advantages and safety of pure laparoscopic hepatectomy in patients with severe damaged liver and cirrhosis.
Three cohorts were evaluated: group I, patients with severe liver damage or cirrhosis (f3-4) who underwent laparoscopic-assisted hepatectomy (n=8); group II, patients with severe liver damage or cirrhosis (f3-4) who underwent pure laparoscopic hepatectomy (n=10); group III, patients with normal liver (f0) who underwent pure laparoscopic hepatectomy (control, n=7). A comparison of operative time, blood loss, serum albumin, C-reactive protein, duration of hospitalization, duration of postoperative indispensable hospitalization, and the duration of ascites drainage was made between the 3 cohorts.
All parameters except for operative time and C-reactive protein investigated were significantly worse in group I compared with the other 2 groups.
In conclusion, pure laparoscopic hepatectomy might be safe for patients with damaged liver and cirrhosis.
Division of Transplantation, Reconstruction and Endoscopic Surgery, Graduate School of Medicine, Tohoku University, Sendai, Japan
Supported by Grants-in-Aid for Scientific Research from the Ministry of Education, Science, and Culture of Japan, and from the Ministry of Welfare of Japan, and by a grant from Tohoku University Graduate School of Medicine.
The authors declare no conflicts of interest.
Reprints: Shigehito Miyagi, MD, PhD, Division of Transplantation, Reconstruction and Endoscopic Surgery, Graduate School of Medicine, Tohoku University, 1-1 Seiryo-machi, Aoba-ku, Sendai 980-8574, Japan (e-mail: email@example.com).
Received September 30, 2014
Accepted March 2, 2015