Surgery for gastroesophageal reflux disease and achalasia is performed to alleviate symptoms by improving esophagogastric junction (EGJ) function. Intraoperative manometry was used to evaluate the pressure-length characteristics of the reconstructed EGJ during laparoscopic Nissen fundoplication and laparoscopic Heller myotomy. Intraoperative manometry was performed in 37 consecutive patients undergoing laparoscopic Nissen fundoplication (n = 22) or laparoscopic Heller myotomy (n = 15). Measurements were taken before surgery, after creation of the pneumoperitoneum, after completion of the myotomy in achalasia, and after creation of the fundoplication. Tracings were analyzed for pressure, length, and the integrated pressure–length relation (area under the curve [AUC]). Statistical comparison was made using paired t tests; intraoperative EGJ measurements did not correlate well with preoperative values for either pressure or length. Laparoscopic Nissen fundoplication significantly increased pressure, length, and AUC of the EGJ compared with prefundoplication values. Laparoscopic Heller myotomy significantly decreased EGJ pressure, length, and AUC. Creation of a Toupet fundoplication after myotomy did not significantly increase pressure, length, and AUC of the EGJ compared with postmyotomy values. Intraoperative manometry identified 2 of 15 achalasia patients (13%) with persistent areas of high pressure after initial myotomy that were corrected by extending the myotomy. Intraoperative manometry identifies mechanical changes created during EGJ surgery and may be a useful adjunct to improve outcomes of laparoscopic Nissen fundoplication and laparoscopic Heller myotomy.
From the Department of Surgery, University of Cincinnati (MSN, TAP, DRF, BW, JB), Cincinnati, Ohio, and the Department of Medicine, Division of Gastroenterology, Northwestern University (MPJ), Chicago, Illinois.
Received February 26, 2001; revision received July 18, 2001; accepted July 20, 2001.
Address correspondence and reprint requests to Dr. Michael S. Nussbaum, University of Cincinnati Medical Center, P. O. Box 670558, 231 Albert Sabin Way, Cincinnati, OH 45267-0558. Address electronic mail to: Nussbams@ucmail.uc.edu
Presented at the annual meeting of the Society of American Gastrointestinal Endoscopic Surgeons (SAGES), Atlanta, Georgia, March 29–April 1, 2000.