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Pre-exposure prophylaxis (PrEP) for HIV prevention among HIV-uninfected pregnant women: estimated coverage using risk-based versus regional prevalence approaches

Pintye, Jillian, PhD1; Singa, Benson, MD2; Wanyonyi, Kennedy, BS2; Itindi, Janet, BS2; Kinuthia, John, MD3; Langat, Agnes, MD4; Nganga, Lucy, MD4; Katana, Abraham, MD4; Baeten, Jared, MD1; McGrath, Christine J., PhD1; John-Stewart, Grace C., MD1

doi: 10.1097/OLQ.0000000000000898
Note/Case Report: PDF Only

Antenatal register data from 62 clinics in 5 regions of Kenya were used to estimate women with HIV risk (partner HIV status, syphilis). With individual risk-guided PrEP offer in all regions, 39% of pregnant women nationally would be offered PrEP. PrEP offer to all women in high prevalence regions would result in 26%.

1University of Washington, Seattle, Washington, USA

2Kenya Medical Research Institute, Nairobi, Kenya

3Kenyatta National Hospital, Nairobi, Kenya

4Centers for Disease Control and Prevention (CDC) Kenya, Nairobi, Kenya

Corresponding author: Jillian Pintye, PhD; University of Washington, Department of Global Health, 325 Ninth Ave., Box 359909, Seattle, WA 98104; Tel: +1-206-543-4278, Fax: +1-206-543-4818, email: jpintye@uw.edu

Funding: President’s Emergency Plan for AIDS Relief (PEPFAR) and Centers for Disease Control and Prevention (COAG#U2GPS002047). JP was supported by a NIH training grant T32AI07140 and F32NR017125. GJS was suppor by a NIH K24 grant (HD054314). The CHIME Team was supported by the University of Washington’s Global Center for Integrated Health of Women Adolescents and Children (Global WACh) and Center for AIDS Research (CFAR) (P30 AI027757).

CDC Disclaimer: The findings and conclusions in this paper are those of the author(s) and do not necessarily represent the official position of the U.S. Centers for Disease Control and Prevention, United States National Institutes of Health and Government of Kenya.

Conflicts of interest: The authors declare that no conflicts of interest exist.

Received for publication May 14, 2018, and accepted July 15, 2018.

© Copyright 2018 American Sexually Transmitted Diseases Association