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Mycoplasma genitalium Coinfection in Women With Chlamydia trachomatis Infection

Harrison, Sally A. BS*; Olson, Kristin M. MPH*,†,‡; Ratliff, Amy E. BS§; Xiao, Li PhD; Van Der Pol, Barbara PhD, MPH; Waites, Ken B. MD§; Geisler, William M. MD, MPH*,†

doi: 10.1097/OLQ.0000000000001028

We evaluated the prevalence of Mycoplasma genitalium coinfection in 302 chlamydia-infected women seen at a sexually transmitted disease clinic in Birmingham, AL. M genitalium coinfection was detected in 22 (7.3%). No participant characteristics predicted coinfection. Among coinfected women, M genitalium was detected again in 6 (28.6%) of 21 women returning for a 3-month follow-up visit after azithromycin treatment.

A study of Mycoplasma genitalium coinfection among 302 chlamydia-infected women seen at a sexually transmitted disease clinic found coinfection in 22 (7.3%). Repeat M genitalium detection at a 3-month follow-up visit occurred in 6 (28.6%) of 21 women.

From the *School of Medicine

Departments of Medicine


§Pathology, University of Alabama at Birmingham, Birmingham, AL

Acknowledgments: The authors would like to thank the University of Alabama at Birmingham clinicians Christen Press and Hanne Harbison for their contributions.

Conflict of Interest and Sources of Funding: L.X. and K.W. report receiving research support paid to their institution from Roche Molecular. B.V.D.P. reports receiving honorarium, consulting fees, or research support paid to her institution from Abbott Molecular, Atlas Genetics, BD Diagnostics, Click Diagnostics, Cepheid, Luminex, Rheonix, and Roche Molecular. W.M.G. reports receiving consulting fees from Hologic, Inc, and Quest Diagnostics for development of educational materials on Mycoplasma genitalium and research support paid to his institution by Hologic Inc. This work was supported by the National Institute of Allergy and Infectious Diseases (award R01AI093692 to W.M.G.) and the Eunice Kennedy Shriver National Institute of Child Health and Human Development (award F31HD094539 to K.M.O.) of the National Institutes of Health.

The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.

Correspondence: William M. Geisler, MD, MPH, UAB STD Program, 703 19th St. South, 242 Zeigler Research Building, Birmingham, AL 35294-0007. E-mail:

Received for publication February 15, 2019, and accepted May 22, 2019.

Online date: June 7, 2019

© Copyright 2019 American Sexually Transmitted Diseases Association