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Heterosexual Men Anticipate Risk Compensatory Behaviors With Future Preexposure Prophylaxis Initiation

Findings From an Exploratory Cross-Sectional Study

Roth, Alexis M. PhD, MPH*; Tran, Nguyen MPH*; Felsher, Marisa DrPHc*; Szep, Zsofia MD; Krakower, Douglas MD

doi: 10.1097/OLQ.0000000000001012
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Among 146 urban heterosexuals screening negative for human immunodeficiency virus, one third anticipated increased sexual risk taking with human immunodeficiency virus preexposure prophylaxis. Men (vs. women) and black (vs. white) participants had increased odds for anticipating decreased condom use. Men and persons reporting transactional sex expected to increase sexual partnerships. Risk compensation could affect reproductive health and disease control.

A substantial minority of urban heterosexuals undergoing human immunodeficiency virus testing anticipated increased sexual risk behaviors if they were to initiate human immunodeficiency virus preexposure prophylaxis, which could affect reproductive health and disease control.

From the *Dornsife School of Public Health, Drexel University

Division of Infectious Diseases and HIV Medicine, Drexel University College of Medicine, Philadelphia, PA

Infectious Diseases/Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA

Conflicts of Interest: none declared.

Sources of Funding: This research was supported by the Drexel School of Public Health/College of Medicine Seed Grant Program. Dr. Roth was supported by the American STD Association Career Award Program. Dr. Krakower was supported by NIMH K23MH098795.

Acknowledgments: The authors would like to thank the participants, our recruitment sites, research assistants, and Dr. Scarlett Bellamy for providing statistical consultation for this article.

Correspondence: Alexis M. Roth, PhD, MPH, Drexel University Dornsife School of Public Health, 3215 Market St, 4th floor Philadelphia, PA 19104. E-mail: alexisroth@drexel.edu.

Received for publication February 21, 2019, and accepted April 21, 2019.

Online date: April 25, 2019

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