Secondary Logo

Journal Logo

Institutional members access full text with Ovid®

Mycoplasma genitalium, Chlamydia trachomatis, and Neisseria gonorrhoeae Detected With Aptima Assays Performed on Self-Obtained Vaginal Swabs and Urine Collected at Home and in a Clinic

Chernesky, Max PhD*; Jang, Dan BSc*; Martin, Irene BSc; Arias, Manuel BSc*; Shah, Anika BSc*; Smieja, Marek MD, PhD*; Ratnam, Sam PhD*; Getman, Damon PhD; Schachter, Julius PhD§

doi: 10.1097/OLQ.0000000000001004

Self-obtained vaginal swabs, first-void urine and pooled specimens were collected at home and in a clinic. Percent prevalence and collection site concordance was 30.3 and 100 for Mycoplasma genitalium (74.4% azithromycin resistant) 15.1 and 96.7 for Chlamydia trachomatis and 6.6 and 100 for Neisseria gonorrhoeae (27% ciprofloxacin-resistant).

Female self-obtained specimens collected and pooled at home and in clinic showed similar detection rates in each setting for Mycoplasma genitalium, Chlamydia trachomatis, and Neisseria gonorrhoeae. Antimicrobial resistance was determined.

From the *St. Joseph's Healthcare/ McMaster University, Hamilton, ON

National Microbiology Laboratory, Winnipeg, MB, Canada

Hologic Inc., San Diego, CA

§University of California, San Francisco, CA

Conflict of Interest: D.G. is a scientist employed by Hologic. All others have no conflict of interest.

Sources of Funding: The analyte-specific reagents for M. genitalium testing and Aptima Combo 2 assay kits were provided by Hologic Inc.

Correspondence: Max Chernesky, St. Joseph's Healthcare, 50 Charlton Ave E, Hamilton, ON, Canada L8N 4A6. E-mail:

Received for publication January 31, 2019, and accepted March 15, 2019.

Online date: April 5, 2019

© Copyright 2019 American Sexually Transmitted Diseases Association