Studies have documented high human immunodeficiency virus (HIV) prevalence among transwomen in the United States; however, to our knowledge, no studies have documented trends in HIV prevalence in this population.
We used respondent-driven sampling to sample transwomen in San Francisco for 3 HIV prevalence and behavioral surveys in 2010, 2013, and 2016. Our analysis of point estimates and trends were weighted for the sampling method.
Human immunodeficiency virus prevalence by serological testing in the survey was 38.8% (95% confidence interval [CI], 32.4–45.2), 33.7% (95% CI, 25.9–41.5), and 31.6% (95% CI, 12.2–38.1) in 2010, 2013, and 2016, respectively. Disparities in higher HIV prevalence by black, Latino, and Asian race/ethnicity and lower education level persisted through 2016.
Based on a statistical test for trend, HIV prevalence among transwomen has remained high and stable from 2010 to 2016. Human immunodeficiency virus infection is still highest at 31.6% compared to any other group in San Francisco. We also observed that older transwomen had significantly higher odds of living with HIV than younger women over the last 2 waves of data collection. Taken together, these trends suggest that there is declining incidence of new HIV infections among low-income transwomen in San Francisco. Moreover, among transwomen, HIV disproportionately affects transwomen of color.
Human immunodeficiency virus prevalence among transwomen has remained high and stable from 2010 to 2016. Older transwomen had higher odds of HIV infection. These trends suggest declining incidence of new human immunodeficiency virus infections among transwomen in San Francisco.
From the *Biostatistics - Epidemiology, School of Public Health, Rutgers University, New Brunswick, NJ;
†Center for Public Health Research, San Francisco Department of Public Health; and
‡Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA
Sources of Funding: This study was partially funded by NIH (grant number 1 R01 MH109397).
Conflict of Interest: None declared.
Ethical approval: All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.
Informed consent was obtained from all individual participants included in the study.
Correspondence: Henry F. Raymond, PhD, 683 Hoes Lane West, Piscataway, NJ 08854. E-mail: Hfisher.email@example.com.
Received for publication June 28, 2018, and accepted September 17, 2018.