In November 2011, the National Institutes of Health convened a workshop of basic researchers, epidemiologists, and clinical experts in pelvic inflammatory disease to identify research gaps hindering advances in diagnosis, treatment, and prevention. This article summarizes the presentations, discussions, and conclusions of this group and highlights significant controversies that reveal aspects of pelvic inflammatory disease research that would most greatly benefit from the application of newer molecular, immunologic, and radiologic techniques. Multiple limitations to performing new clinical trials exist; however, emerging data from ongoing clinical trials will add to the current body of knowledge regarding prevention and treatment strategies. In addition, use of established health care databases could serve as a valuable tool for performance of unbiased epidemiologic outcome studies.
This study aimed to identify research gaps among proceedings of a 2011 National Institutes of Health–sponsored workshop on pelvic inflammatory disease where past and recent data were reviewed and goals were defined for future research.
From the Department of Pediatrics, Children’s Hospital of Pittsburgh and University of Pittsburgh Medical Center, Pittsburgh, PA; and
The Pelvic Inflammatory Disease Workshop Proceedings Committee.
Acknowledgments: The authors acknowledge the support and contribution of Marcia Hobbs, M. Elizabeth Rogers, the National Institutes of Health (NIH)–funded Sexually Transmitted Infections Cooperative Research Center investigators and other participants of the NIH-sponsored Pelvic Inflammatory Disease workshop.
Dr Darville has no conflict of interest.
Dr Toni Darville is supported by US NIH Grants (AI054624 and U19 AI084024).
Correspondence: Toni Darville, MD, Children’s Hospital Drive, 45th St and Penn Ave, Pittsburgh, PA 15201. E-mail: firstname.lastname@example.org.
Received for publication January 3, 2013, and accepted July 22, 2013.