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Recurrent PID, Subsequent STI, and Reproductive Health Outcomes: Findings From the PID Evaluation and Clinical Health (PEACH) Study

Trent, Maria MD, MPH*; Bass, Debra MS; Ness, Roberta B. MD, MPH; Haggerty, Catherine PhD, MPH

doi: 10.1097/OLQ.0b013e31821f918c

PEACH trial data were used to evaluate the relationship between subsequent sexually transmitted infection and recurrent pelvic inflammatory disease on infertility and chronic pelvic pain (CPP). Recurrent pelvic inflammatory disease was associated with an almost 2-fold increase in infertility and more than 4-fold increase in CPP. Subsequent sexually transmitted infection was associated with CPP, but not infertility.

Longitudinal follow-up of women in the PEACH trial substantiates the established relationship between recurrent PID, subsequent lower genital tract infection, and adverse sequelae despite recent observations in the microbiology of PID.

From the *Department of Pediatrics, Johns Hopkins School of Medicine, Baltimore, MD; †Department of Reproductive Epidemiology, University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA; and ‡University of Texas School of Public Health, Houston, TX

Correspondence: Maria Trent, MD, MPH, Department of Pediatrics, Johns Hopkins School of Medicine, 200 N. Wolfe St, 2064, Baltimore, MD 21287. E-mail:

Received for publication November 15, 2010, and accepted April 13, 2011.

© Copyright 2011 American Sexually Transmitted Diseases Association