Institutional members access full text with Ovid®

Share this article on:

Asymptomatic Gonorrhea and Chlamydial Infections Detected by Nucleic Acid Amplification Tests Among Boston Area Men Who Have Sex With Men

Mimiaga, Matthew J. ScD, MPH*†; Mayer, Kenneth H. MD*‡;; Reisner, Sari L. MA*; Gonzalez, Alex MD, MPH*; Dumas, Bill RN§; Vanderwarker, Rodney BA*; Novak, David S. MSW§; Bertrand, Thomas MPH§

Sexually Transmitted Diseases: May 2008 - Volume 35 - Issue 5 - p 495-498
doi: 10.1097/OLQ.0b013e31816471ae

Background: The purpose of this project was to determine the prevalence of asymptomatic sexually transmitted diseases (STDs) among men who have sex with men (MSM) in the Boston area who had been sexually active (oral and/or anal sex) with another male within the past year.

Methods: Over a 1-month period (March 2007), asymptomatic MSM in care at a Boston community health center (n = 114) were screened for gonorrhea and chlamydia using the BD ProbeTec technique. Deidentified medical record data were analyzed and linked to prevalence monitoring results.

Results: Eleven percent of the sample tested positive for one of the 2 STDs (gonorrhea or chlamydia) from at least one mucosal site. Individuals who were infected with an STD were considerably more likely to have a prior history of one or more STD infections when compared with those without an STD history (OR = 3.69; P <0.02). There were no significant differences observed in psychosocial and other behavioral risk factors between patients with or without an STD.

Conclusions: Screening asymptomatic MSM using nucleic acid amplification tests (NAATs) revealed a substantial STD burden that might not have been diagnosed using traditional assays. These data are critical for the design of effective public health interventions for this population.

This project was to determine the prevalence of asymptomatic STDs (chlamydia and gonorrhea) among men who have sex with men in the Boston area using nucleic acid amplification tests.

From the *The Fenway Institute, Fenway Community Health, Boston, Massachusetts; † Harvard Medical School/Massachusetts General Hospital, Boston, Massachusetts; ‡ Brown Medical School/Miriam Hospital, Providence, Rhode Island; § The Massachusetts Department of Public Health, Boston, Massachusetts

The authors thank the Medical Department of Fenway Community Health for their diligent assistance with participant recruitment, and the much missed Dr. Sylvie Ratelle for her oversight and expertise with protocol development.

Correspondence: Matthew J. Mimiaga, The Fenway Institute, Research and Evaluation Department, Fenway Community Health, Prudential Tower, 4th floor, 800 Boylston Street, Boston, MA 02119. E-mail:

Received for publication August 30, 2007, and accepted November 26, 2007.

© Copyright 2008 American Sexually Transmitted Diseases Association