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Spontaneous HIV-1 Seroreversion in an Adult Male

Coyne, Katherine M.*; Parry, John V.; Atkins, Mark; Pozniak, Anton*; McOwan, Alan*

doi: 10.1097/01.olq.0000258315.91807.70

A man developed HIV-1 antibodies, which disappeared spontaneously. He had negative HIV viral load and p24 antigen tests and did not develop immunosuppression. Further investigations suggest the HIV-positive result was a nonspecific reaction. An alternative explanation is that he was exposed to HIV and had a “near-miss” HIV infection.

A man developed HIV-1 antibodies, which disappeared spontaneously. Further investigations suggest that this was a nonspecific reaction.

From the *HIV/GUM Directorate, Chelsea and Westminster Healthcare NHS Trust, London SW10 9NH, United Kingdom; †Centre for Infections, Health Protection Agency, London NW9 5HT United Kingdom; ‡Department of Virology, Hammersmith Hospitals NHS Trust, London W12 0HS United Kingdom

Correspondence: Dr. Katherine M. Coyne, Specialist Registrar in HIV/GUM, St Stephen's Centre, Chelsea & Westminster Hospital, 369 Fulham Road, London, SW10 9NH, United Kingdom. E-mail:

Received August 30, 2006, and accepted November 29, 2006.

© Copyright 2007 American Sexually Transmitted Diseases Association