Review ArticlesSurgical Treatment of Combined ACL, PCL, and Lateral Side InjuriesStannard, James P. MD*,†; Stannard, James T. PhD†,‡; Cook, James L. DVM, PhD*,†Author Information *Department of Orthopaedic Surgery †Thompson Laboratory for Regenerative Orthopaedics, University of Missouri ‡University of Missouri School of Medicine, Columbia, MO Disclosure: The authors declare no conflict of interest. Reprints: James P. Stannard, MD, Department of Orthopaedic Surgery, Missouri Orthopaedic Institute, University of Missouri, 1100 Virginia Avenue, Columbia, MO 65212. Sports Medicine and Arthroscopy Review: September 2020 - Volume 28 - Issue 3 - p 94-99 doi: 10.1097/JSA.0000000000000275 Buy Metrics Abstract A knee dislocation that involves at least 2 of the 4 major ligament groups—such as the anterior cruciate ligament, the posterior cruciate ligament, or the posterolateral corner—is a catastrophic event for an athlete or trauma patient. Careful evaluation of these patients is needed to avoid disastrous outcomes. Surgeons must be cognizant of a number of key treatment concerns—such as tunnel crowding, controversies over graft fixation methods, and sparsity of level I clinical data—to make proper ligament repair decisions. This manuscript will review treatment principles that govern high-quality care of this complex injury. Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.