Review ArticlesOverview of Procurement, Processing, and Sterilization of Soft Tissue Allografts for Sports MedicineSuarez, Luis Sierra MD*; Richmond, John C. MD† ‡Author Information *Instituto Nacional de Rehabilitación, Mexico City, Mexico †Orthopedic Surgery, New England Baptist Hospital ‡Orthopedic Surgery, Tufts University School of Medicine, Boston, MA Reprints: John C. Richmond, MD, New England Baptist Hospital, 125 Parker Hill Avenue, Boston, MA 02120 (e-mail: firstname.lastname@example.org). Sports Medicine and Arthroscopy Review: September 2007 - Volume 15 - Issue 3 - p 106-113 doi: 10.1097/JSA.0b013e3180dca1fe Buy Metrics Abstract Musculoskeletal allografts are commonly used in orthopedic surgery and have become increasingly popular. Their indications have widened as an alternatives to autografts. A tissue processing industry has secondarily evolved. An increasing number of accredited tissue banks are providing donor screening, procurement, processing, storage, and distribution of tissue. Multiple factors play a role for a graft to be successfully implanted: sterility, reduction of antigenicity, and preservation of its biologic and biomechanical properties. A rare but catastrophic complication that has raised concern is disease transmission. Controversies exist on which is the best way to produce a strong, disease-free graft. There is no current standard, but as allograft technology evolves, surgeons need to be aware of the regulations and policies surrounding allograft tissue procurement and processing to provide the best outcomes in transplanted patients. © 2007 Lippincott Williams & Wilkins, Inc.