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00152232-200911001-00048AbstractSpine: Affiliated Society Meeting AbstractsSpine: Affiliated Society Meeting Abstracts© 2009 Lippincott Williams & Wilkins, Inc.November 2009 p THE EFFECT OF DC-STIMULATION ON LUMBAR SPINAL FUSION IN OLDER PATIENTS. A RANDOMIZED CLINICAL MULTI-CENTER TRIAL.2009 Abstract SubmissionAndersen, Thomas1; Christensen, Finn B.1; Ernst, Carsten2; Fruensgaard, Søren3; Østergaard, Jørgen4; Andersen, Jens Langer2; Rasmussen, Sten5; Niedermann, Bent1; Høy, Kristian1; Helmig, Peter1; Holm, Randi1; Lindblad, Bent Erling1; Hansen, Ebbe Stender1; Egund, Niels6; Bünger, Cody11 Orthopaedic Department E, Spine Section, Aarhus University Hospital.2 Orthopaedic Department, Esbjerg County Hospital.3 Orthopaedic Department, Holstebro County Hospital.4 Orthopaedic Department, Viborg County Hospital.5 Orthopaedic Department, Vejle County Hospital.6 Department of Radiology R, Aarhus University Hospital.Submitted Thu, 13 Nov 2008 15:21:16 -0500Presenter's Name Thomas AndersenAuthor for Correspondence Thomas AndersenAuthor's Address Nørrebrogade 44, Build 1A Aarhus, DK-8000 C DenmarkAuthor's Phone +4589494134Author's Fax +4589494150Author's [email protected] Type OriginalPermission to Publish YesPresentation Type Paper_or_PosterCategory 13. SurgeryWord Count 295IntroductionOlder patients experience increased risk of complications and lower fusion rates after spinal fusion surgery. Treatments improving functional outcome and fusion rates without lengthening the procedure could prove beneficial. One option could be direct current (DC) electrical stimulation. The aim of the present study was to investigate the effect of DC-stimulation on functional outcome and fusion rates after lumbar spinal fusion in patients older than 60 years.MethodsA randomised clinical trial comprising five orthopaedic centers. The study included a total of 107 patients randomised to uninstrumented posterolateral lumbar spinal fusion with or without DC-stimulation. Fusion rate was assessed at two year follow-up using thin slice CT. Functional outcome was assessed using Dallas Pain Questionnaire (DPQ), SF-36 and Low Back Pain Rating Scale pain index (LBPRS).ResultsFollow-up after 1 year was 95/107 (89%). DC-stimulated patients had significant better outcome in 3 out of 4 categories in the DPQ, better SF-36 scores (not significantly), but no difference in pain scores were observed. Median walking distance at latest follow-up was better in the stimulated group (not significant). Walking distance was significantly associated with functional outcome. Fusion rates were surprisingly low. DC-stimulation had no effect on fusion rate: 35% versus 36% in controls. Other factors associated with low fusion rates were female gender (32% versus 42% in males, p=0.050) and smoking (21% versus 42% in non-smokers, p=0.079). Patients who achieved a solid fusion as determined by CT had superior functional outcome and pain scores at their latest follow-up.DiscussionDC-stimulated patients tended to have better functional outcome as compared to controls. Thin slice CT revealed very high non-union rates after uninstrumented spinal fusion in older patients, without any effect of DC-stimulation on fusion rates. The achievement of a solid fusion was associated with superior functional outcome.<strong xmlns:mrws="http://webservices.ovid.com/mrws/1.0">THE EFFECT OF DC-STIMULATION ON LUMBAR SPINAL FUSION IN OLDER PATIENTS. A RANDOMIZED CLINICAL MULTI-CENTER TRIAL.</strong>Andersen Thomas; Christensen, Finn B.; Ernst, Carsten; Fruensgaard, Søren; Østergaard, Jørgen; Andersen, Jens Langer; Rasmussen, Sten; Niedermann, Bent; Høy, Kristian; Helmig, Peter; Holm, Randi; Lindblad, Bent Erling; Hansen, Ebbe Stender; Egund, Niels; Bünger, Cody2009 Abstract Submission2009 Abstract Submission